The tourism and hospitality management literature related to innovation has grown substantially in past decades, producing an overarching view of this topic. Studies have highlighted the need for comprehensive empirical evidence to advance innovation. This paper addresses this gap through a quantitative meta-analysis of tourism and hospitality innovation research. The primary objective is to provide an integrated sense of organization-level innovation by synthesizing existing work. This study deepens the understanding of innovation by examining the moderating roles of innovation-related magnitudes (radical and incremental) and types (product, process, organizational, marketing). Findings are presented via a multidimensional framework of innovation and complexity theory; this model comprises 30 managerial factors, five leadership styles, and six environmental factors based on a synthesis of 178 independent studies with 705 estimated relationships. Results offer valuable insights for practitioners and enrich the scholarly picture of organization-level innovation.