{"id":29,"date":"2018-08-21T15:14:04","date_gmt":"2018-08-21T19:14:04","guid":{"rendered":"https:\/\/sites.temple.edu\/kwang\/?page_id=29"},"modified":"2026-01-05T14:45:39","modified_gmt":"2026-01-05T19:45:39","slug":"publications","status":"publish","type":"page","link":"https:\/\/sites.temple.edu\/kwang\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"

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29. N Albeltagy, J Patten, K Wang<\/small>. The interplay between stiffness and hyperglycemia on diabetic foot ulcer wound closure<\/a>. Cellular and Molecular Bioengineering. (2026). https:\/\/doi.org\/10.1007\/s12195-025-00877-8<\/small><\/p>\n

28. J Patten, N Albeltagy, JD Bonadio, A Ortez, K Wang<\/small>. FAK Differentially Mechanoregulates Cell Migration During Wound Closure<\/a>. ACS Biomaterials Science & Engineering. 11(8), 4968-4977 (2025).\u00a0<\/small><\/p>\n

27. J Patten, Patrick Halligan, Ghazal Bashiri, Michael Kegel, Jacob D Bonadio, K Wang. EDA Fibronectin Microarchitecture and YAP Translocation During Wound Closure<\/a>. ACS Biomaterials Science & Engineering. 11(<\/span>4)<\/span>\u00a02249\u20132262 <\/span>(2025).\u00a0<\/small><\/p>\n

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26. L Xue, G Zhao, X Xiong, G Zhao, W Molina-Arocho, R Palanki, Z Xiao, X Han, I-C Yoon, CG Figueroa-Espada, J Xu, Ngong, Q Shi, Z Chen, M-G Alameh, AE Vaughan, M Haldar, K Wang, D Weissman, MJ Mitchell.<\/b> Multiarm-Assisted Design of Dendron-like Degradable Ionizable Lipids Facilitates Systemic mRNA Delivery to the Spleen<\/a>. J American Chemical Society. 147(2) 1542-1552 <\/i><\/b>(2025).<\/b><\/small><\/p>\n<\/div>\n

25. J Patten, K Wang. On the right track<\/a>. Nature Physics. 20: 1702-1703 (2024).<\/small><\/p>\n

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24. L Xue, G Zhao, N Gong, X Han, SJ Sheperd, X Xiong, Z Xiao, R Palanki, J Xu, KL Swingle, CC Warzecha, R El-Mayta, V Chowdhary, I-C Yoon, J Xu, J Cui, Y Shi, M-G Alameh, K Wang, L Wang, DJ Pochan, D Weissman, AE Vaughan, JM Wilson, MJ Mitchell. Combinatorial Design of Siloxane-Incorporated Lipid Nanoparticles Augment Intracellular Processing for Tissue-Specific mRNA Therapeutic Delivery<\/a>. Nature Nanotechnology. 20(1):132-143 (2025).<\/small><\/p>\n<\/div>\n

23. J D. Bonadio, G Bashiri, P Halligan, M Kegel, F Ahmed, K Wang. Delivery technologies for therapeutic targeting of fibronectin in autoimmunity and fibrosis applications<\/a>. Advanced Drug Delivery Reviews. 209: 115303 (2024).\u00a0<\/small><\/p>\n

22. J Longstreth, K Wang. The role of fibronectin in mediating cell migration<\/a>. American Journal of Physiology – Cell Physiology. 326(4): C1212-C1225 (2024).\u00a0<\/i><\/small><\/p>\n

21. L Xue, AG Hamilton, G Zhao, Z Xiao, R El-Mayta, X Han, N Gong, X Xiong, J Xu, CG Figueroa-Espada, SJ Shepherd, AJ Mukalel, M-G Alameh, J Cui, K Wang, AE Vaughan, D Weissman, MJ Mitchell. High-throughput barcoded nanoparticles identify cationic, degradable lipid-like materials for mRNA delivery to the lungs of female preclinical models<\/a>. Nature Communications. 15:1884 (2024).<\/small><\/p>\n

20. L Xue*, AS Thatte*, D Mai, RM Haley, N Gong, X Han, K Wang, NC Sheppard, CH June, MJ Mitchell. Responsive Biomaterials: Optimizing Control of Cancer Immunotherapy<\/a>. Nature Reviews Materials. 9: 100-118 (2024).<\/small><\/p>\n

19. <\/span><\/small>C Figueroa-Espada, P PG Guimaraes, R Riley, L Xue, K Wang<\/small>, MJ Mitchell. siRNA Lipid-Polymer Nanoparticles Targeting E-Selectin and Cyclophilin A in Bone Marrow for Combination Multiple Myeloma Therap<\/a>y. <\/small>Cellular and Molecular Bioengineering<\/small>. <\/small>16: 383-392 (2023)<\/small>.<\/p>\n

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18. P PG Guimaraes, C Figueroa-Espada, R Riley, N Gong, L Xue, T Sewastianik, P Dennis, C Loebel, A Chung, SJ Shepherd, R Haley, A Hamilton, R El-Mayta, K Wang<\/small>, RS Langer, DG Anderson, RD Carrasco, MJ Mitchell. In Vivo Bone Marrow Microenvironment siRNA Delivery Using Lipid-Polymer Nanoparticles for Multiple Myeloma Therapy<\/a>. <\/small>Proceedings of the National Academy of Sciences. <\/small>120 (25) e2215711120 (2023)<\/small>.<\/small><\/p>\n

17.\u00a0<\/small>G Bashiri, M Padilla, KL Swingle, SJ Shepherd, MJ Mitchell, K Wang. Nanoparticle Protein Corona: From Structure and Function to Therapeutic Targeting<\/a>. Lab on a Chip. 23: 1432-1466 (2023).\u00a0<\/small><\/p>\n

16. K Butowska, X Han, N Gong, R El-Mayta, RM Haley, L Xue, W Zhong, W Guo, K Wang, MJ Mitchell. Doxorubicin-conjugated siRNA lipid nanoparticles for combination cancer therapy<\/a>. Acta Pharmaceutica Sinica B. 13(4): 1429-1437 (2023).<\/span><\/p>\n

15. L Xue, N Gong, SJ Shepard, X Xiong, X Liao, X Han, G Zhao, C Song, X Huang, H Zhang, MS Padilla, J Qin, Y Shi, M-G Alameh, DJ Pochan, K Wang, F Long, D Weissman, MJ Mitchell. Rational design of bisphosphonate lipid-like materials for mRNA delivery to the bone microenvironment.<\/a> Journal of the American Chemical Society. 144(22): 9926-9937 (2022).<\/span><\/p>\n

14. SK Patel, MM Billingsley, C Frazee, X Han, KL Swingle, J Qin, M-G Alameh, K Wang, D Weissman, MJ Mitchell. Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells<\/a>. Journal of Controlled Release. 347: 521-532 (2022).<\/span><\/p>\n

13. J Patten, K Wang. Fibronectin in development and wound healing.<\/a> Advanced Drug Delivery Reviews. 170: 353-368 (2021). <\/span><\/p>\n

12.\u00a0M Krohn-Grimberghe, MJ Mitchell, MJ Schloss, OF Khan, G Courties, PPG Guimaraes, D Rohde, S Cremer, PS Kowalski, Y Sun, M Tan, J Webster, K Wang, Y Iwamoto, SP Schmidt, GR Wojtkiewicz, R Nayar, V Frodermann, M Hulsmans, A Chung, FF Hoyer, FK Swirski, R Langer, DG Anderson, M Nahrendorf. Nanoparticle-encapsulated siRNAs for gene silencing in the haematopoietic stem-cell niche<\/a>. Nature Biomedical Engineering. (2020). https:\/\/doi.org\/10.1038\/s41551-020-00623-7\u00a0<\/span><\/p>\n

11. BR Seo, X Chen, L Ling, AA Shimpi, YH Song, L Ling, S Choi, J Gonzalez, J Sapudom, K Wang, RCA Eguiluz, D Gourdon, V Shenoy, C Fischbach. <\/span>Collagen microarchitecture mechanically controls myofibroblast differentiation<\/small><\/a>. Proceedings of the National Academy of Sciences.\u00a0117(21): 11387-11398 (2020).<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n

10.\u00a0<\/span>JH Kim, AF Pegoraro, A Das, S Koehler, SA Ujwary, B Lan, JA Mitchel, L Atia, S He, K Wang, D Bi, M Zaman, J-A Park, JP Butler, KH Lee, JR Starr, JJ Fredberg. Unjamming and collective migration in MCF10A breast cancer cell lines.<\/a> Biochemical and Biophysical Research Communications.\u00a0521(3): 706-715 (2020).\u00a0<\/span><\/p>\n

9. PPG Guimaraes, M Tan, T Tammela, K Wu, A Chung, M Oberli, K Wang, R Spektor, RS Riley, CTR Viana, T Jacks, R Langer, MJ Mitchell. Potent in vivo lung cancer Wnt signaling inhibition via cyclodextrin-LGK974 inclusion complexes.<\/a> Journal of Controlled Release. 290: 75-87 (2018).<\/span><\/p>\n

8. K Wang, F Wu, BR Seo, C Fischbach, W Chen, L Hsu, D Gourdon. Breast cancer cells alter the dynamics of stromal fibronectin-collagen interactions.<\/a> Matrix Biology.60-61: 86-95 (2017).<\/span><\/p>\n

7. K Wang, L-H Cai, B Lan, JJ Fredberg. Hidden in the mist no more: physical force in cell biology.<\/a> Nature Methods. 13: 124-125 (2016).<\/span><\/p>\n

6. K Wang, BR Seo, C Fischbach, D Gourdon. Fibronectin mechanobiology regulates tumorigenesis.<\/a> Cellular and Molecular Bioengineering.9: 1-11 (2016). *2017 CMBE Most Downloaded Article Award at BMES*<\/span><\/p>\n

5. BR Seo, P Bhardwaj, S Choi, J. Gonzalez, RC Andresen Eguiluz, K Wang, S. Mohanan, PG Morris, B Du, XK Zhou, LT Vahdat, A Verma, O Elemento, CA Hudis, RM Williams, D Gourdon, AJ Dannenberg, C Fischbach. Obesity-dependent changes in interstitial ECM mechanics promote breast tumorigenesis.<\/a> Science Translational Medicine.7(301):301ra130 (2015).<\/span><\/p>\n

4. AMD Wan, S Inal, T Williams, K Wang, P Leleux, L Estevez, CK Ober, EP Giannelis, C Fischbach, GG Malliaras, D Gourdon. 3D Conducting Polymer Platforms for Electrical Control of Protein Conformation and Cellular Functions.<\/a> Journal of Materials Chemistry Part B & C. 3:5040-5048 (2015).<\/span><\/p>\n

3. K Wang*, RC Andresen Eguiluz*, F Wu, BR Seo, C Fischbach, D Gourdon. Stiffening and unfolding of early deposited-fibronectin increase proangiogenic factor secretion by breast cancer-associated stromal cells.<\/a> Biomaterials. 54: 63-71(2015). * Authors contributed equally<\/span><\/p>\n

2. TM D’Alfonso, K Wang, YL Chiu, SJ Shin. Pathologic Upgrade Rates on Subsequent Excision When Lobular Carcinoma In Situ Is the Primary Diagnosis in the Needle Core Biopsy With Special Attention to the Radiographic Target.<\/a> Archives of Pathology & Laboratory Medicine. 137(7): 927-935 (2013).<\/span><\/p>\n

1. C Hashi, Y Zhu, GY Yan, WL Young, BS Hsiao, K Wang, B Chu, S Li. Antithrombogenic property of bone marrow mesenchymal stem cells in nanofibrous vascular grafts.<\/a> Proceedings of the National Academy of Sciences. 104(29): 11915-11920 (2007).<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

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