{"id":27,"date":"2020-02-28T03:37:55","date_gmt":"2020-02-28T03:37:55","guid":{"rendered":"https:\/\/icterm.wordpress.com\/?page_id=27"},"modified":"2024-08-01T10:40:50","modified_gmt":"2024-08-01T14:40:50","slug":"research","status":"publish","type":"page","link":"https:\/\/sites.temple.edu\/icterm\/research\/","title":{"rendered":"Research Topics"},"content":{"rendered":"\n
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Bioreactor Fabrication for Organoid Culture<\/h3>\n\n\n\n

Our lab designs and uses custom bioreactors for organoid development and stem cell differentiation. Current research involves creating systems using modified HARVs (High Aspect Ratio Vessels) as well as novel devices for use in a Random Positioning Machine. Both are devices meant to model microgravity.<\/p>\n<\/div>\n\n\n\n

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Phelan et al. Stem Cell Investig . 2018 Oct 10;5:33. doi: 10.21037\/sci.2018.09.06<\/figcaption><\/figure>\n<\/div>\n<\/div>\n\n\n\n
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3D Bioprinting<\/h3>\n\n\n\n

Bioprinting is an amazing technology that allows researchers to create complex biomimetic structures. <\/p>\n<\/div>\n\n\n\n

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Azadeh Timnak et al 2018 Biomed. Mater. 13 065010<\/figcaption><\/figure>\n<\/div>\n\n\n\n
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Electrospinning Organic Scaffolds<\/h3>\n\n\n\n

This project involves using electrospinning\/electroblowing techniques to create fibrous scaffolds out of organic molecules, primarily soy. These can be used for skin would healing as well as bone regeneration.<\/p>\n<\/div>\n<\/div>\n\n\n\n

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Effects of altered gravity on osteogenic cells<\/h3>\n\n\n\n

We study the effects that low gravity have on osteogenic (bone) cells in the hopes of rescuing the effect that low gravity has on an astronaut’s bones. <\/p>\n<\/div>\n\n\n\n

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Computational Modeling<\/h3>\n\n\n\n

We perform computation modeling for many purposes, including:
– Stem cell growth and differentiation
– 3D cell aggregation
– Bioreactor fluid dynamics
– Electric field simulation for bioreactors and electrospinning<\/p>\n<\/div>\n\n\n\n

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Recent Publications<\/h2>\n\n\n\n