Publications

YAP regulates the self-organized fate patterning of hESC-derived gastruloids.

Stronati E, Giraldez S,Huang L, Abraham E, McGuire GR, Hsu HT, Jones KA, Estaras C.

Stem Cell Reports, 2022 Feb https://doi.org/10.1016/j.stemcr.2021.12.012

Specifying the Anterior Primitive Streak by Modulating YAP1 Levels in Human Pluripotent Stem Cells.

Hsu HT, Estarás C, Huang L, Jones KA.

Stem Cell Reports. 2018 Dec 11;11(6):1357-1364. doi: 10.1016/j.stemcr.2018.10.013. Epub 2018 Nov 15.

Lineage specific transcription factors and epigenetic regulators mediate TGFβ-dependent enhancer activation.

Fueyo R, Iacobucci S, Pappa S, Estarás C, Lois S, Vicioso-Mantis M, Navarro C, Cruz-Molina S, Reyes JC, Rada-Iglesias Á, de la Cruz X, Martínez-Balbás MA.

Nucleic Acids Res. 2018 Apr 20;46(7):3351-3365. doi: 10.1093/nar/gky093.

YAP repression of the WNT3 gene controls hESC differentiation along the cardiac mesoderm lineage.

Estarás C, Hsu HT, Huang L, Jones KA.

Genes Dev. 2017 Nov 15;31(22):2250-2263. doi: 10.1101/gad.307512.117. Epub 2017 Dec 21.

EZH2 regulates neuroepithelium structure and neuroblast proliferation by repressing p21.

Akizu N, García MA, Estarás C, Fueyo R, Badosa C, de la Cruz X, Martínez-Balbás MA.

Open Biol. 2016 Apr;6(4):150227. doi: 10.1098/rsob.150227. Epub 2016 Apr 20.

SMADs and YAP compete to control elongation of β-catenin:LEF-1-recruited RNAPII during hESC differentiation.

Estarás C, Benner C, Jones KA.

Mol Cell. 2015 Jun 4;58(5):780-93. doi: 10.1016/j.molcel.2015.04.001. Epub 2015 Apr 30

A gene-specific role for the Ssu72 RNAPII CTD phosphatase in HIV-1 Tat transactivation.

Chen Y, Zhang L, Estarás C, Choi SH, Moreno L Jr, Karn J, Moresco JJ, Yates JR 3rd, Jones KA.

Genes Dev. 2014 Oct 15;28(20):2261-75. doi: 10.1101/gad.250449.114

Regulation of CBP and Tip60 coordinates histone acetylation at local and global levels during Ras-induced transformation.

Sánchez-Molina S, Estarás C, Oliva JL, Akizu N, Asensio-Juan E, Rojas JM, Martínez-Balbás MA.

Carcinogenesis. 2014 Oct;35(10):2194-202. doi: 10.1093/carcin/bgu111. Epub 2014 May 22.

An increase in MECP2 dosage impairs neural tube formation.

Petazzi P, Akizu N, García A, Estarás C, Martínez de Paz A, Rodríguez-Paredes M, Martínez-Balbás MA, Huertas D, Esteller M.

Neurobiol Dis. 2014 Jul;67:49-56. doi: 10.1016/j.nbd.2014.03.009. Epub 2014 Mar 19

α-Catenin interacts with APC to regulate β-catenin proteolysis and transcriptional repression of Wnt target genes.

Choi SH, Estarás C, Moresco JJ, Yates JR 3rd, Jones KA.

Genes Dev. 2013 Nov 15;27(22):2473-88. doi: 10.1101/gad.229062.113.

RNA polymerase II progression through H3K27me3-enriched gene bodies requires JMJD3 histone demethylase.

Estarás C, Fueyo R, Akizu N, Beltrán S, Martínez-Balbás MA.

Mol Biol Cell. 2013 Feb;24(3):351-60. doi: 10.1091/mbc.E12-07-0561. Epub 2012 Dec 14.

Genome-wide analysis reveals that Smad3 and JMJD3 HDM co-activate the neural developmental program.

Estarás C, Akizu N, García A, Beltrán S, de la Cruz X, Martínez-Balbás MA.

Development. 2012 Aug;139(15):2681-91. doi: 10.1242/dev.078345.

Epithelial-mesenchymal transition can suppress major attributes of human epithelial tumor-initiating cells.

Celià-Terrassa T, Meca-Cortés O, Mateo F, Martínez de Paz A, Rubio N, Arnal-Estapé A, Ell BJ, Bermudo R, Díaz A, Guerra-Rebollo M, Lozano JJ, Estarás C, Ulloa C, Álvarez-Simón D, Milà J, Vilella R, Paciucci R, Martínez-Balbás M, de Herreros AG, Gomis RR, Kang Y, Blanco J, Fernández PL, Thomson TM.

J Clin Invest. 2012 May;122(5):1849-68. doi: 10.1172/JCI59218. Epub 2012 Apr 16.

H3K27me3 regulates BMP activity in developing spinal cord.

Akizu N, Estarás C, Guerrero L, Martí E, Martínez-Balbás MA.

Development. 2010 Sep 1;137(17):2915-25. doi: 10.1242/dev.049395. Epub 2010 Jul 28.

Involvement of chromatin and histone deacetylation in SV40 T antigen transcription regulation.

Valls E, Blanco-García N, Aquizu N, Piedra D, Estarás C, de la Cruz X, Martínez-Balbás MA.

Nucleic Acids Res. 2007;35(6):1958-68. Epub 2007 Mar 6.