I was born and raised in Tasmania, Australia. My first experience of research at the Australian Antarctic Division in my native Tasmania was a turning point that led me to move to Canberra to study at the Australian National University. I completed my honors research with Drs Ron Pace, Elmars Krausz and Tom Wydrzynski on near-infrared spectroscopy of Photosystem II, the intergral membrane protein responsible for oxygen evolution in photosynthesis. This in turn excited my interest in protein structure, and I moved to the University of Chicago to pursue my Ph.D. with Profs James Norris and Keith Moffat on time-resolved crystallography of the bacterial photosynthetic reaction center.
I continued my research on protein structure as a postdoctoral fellow in the laboratory of Prof. Johann Deisenhofer at UT Southwestern Medical Center. There I determined the first structure of an invertebrate thioester-containing protein, thioester-containing protein 1 from Anopheles gambiae TEP1, and a heterodimeric complex of leucine-rich repeat proteins LRIM1/APL1C that regulate TEP1 activity. As an Assistant Professor at Yale University (2010-17) and now Temple University School of Medicine I continue to analyze molecular mechanisms of complement-like immunity in insects and their roles in inflammation, autophagy, and transmission of vector-borne diseases.
|1998||B.Sc.(Hons.), Australian National University|
|2004||Ph.D., University of Chicago|
|2004-10||Postdoctoral Fellow, Dept. of Biochemistry, UT Southwestern Medical Center|
|2010-||Assistant Professor, Dept. of Chemistry, Yale University|
Click here to access my publication list at NCBI.
Honors and Awards
|1993||National Undergraduate Scholarship, Australian National University|
|1998||University Medal in Chemistry, Australian National University|
|1998||Brian Ledley Scholarship, University of Chicago|
|2002||Burroughs Wellcome Interfaces Program Training Fellowship, University of Chicago|
|2004||Student Research Achievement Award, 48th Annual Biophysical Society Meeting|
|2004||Elizabeth Norton Prize for Excellence in Research, Chemistry Dept., University of Chicago|
|2008||Postdoctoral Poster Prize, 13th Annual Structural Biology Symposium, UTMB, Galveston|
|2009||Boomerang Award, Australian Society for Biochemistry & Molecular Biology|